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Phase I trial will leverage GlymaxX cancer cell-killing enhancement antibody technology
May 24, 2018
By: Kristin Brooks
Managing Editor, Contract Pharma
ProBioGen AG has achieved an undisclosed milestone payment from Merus N.V. based on Merus’ use of MCLA-158, a bispecific antibody using the GlymaxX antibody-dependent cell-mediated cytotoxicity (ADCC)-enhancing technology in its Phase I trial. The trial in patients with solid tumors will initially focus on metastatic colorectal cancer. MCLA-158 uses ProBioGen’s GlymaxX technology for greater cell-killing potential. GlymaxX is a stable modification, applicable to any producer cell, leading them t...
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